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In a rat model of neuropathic pain induced by tight ligation of L5/L6 spinal nerves, morroniside, administered either orally or intrathecally, dose-dependently alleviated mechanical allodynia, with comparable maximal efficacy (E max ) and an effective dose 50% (ED 50 ) values of 335 mgkg (oral) and 7.1 g (intrathecal) [73]

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Possible Side Effects Mild injection-site reactions (redness, itching) with subcutaneous administration

If it's not, it may not be undergoing inspections or complying with other laws

Neuronal high oxygen use results in the brain being at increased risk from an imbalance in this system (Murray et al