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10.1016/j.neuro.2021.10.003 134 SongM
Tirzepatide vs semaglutide: Which is more effective for weight loss
The acylation modification gives retatrutide a half-life of approximately six days, allowing once-weekly dosing, but that long half-life also means dosing errors compound over time rather than resolving quickly
Furthermore, the 5 mg, 10 mg, and 15 mg doses exhibited superior weight loss and glycemic control relative to dulaglutide (1.5 mg), while maintaining an acceptable safety and tolerability profile
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