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Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

Foundayo (ATTAIN-1 trial) was far larger, with 3,127 adults in the same broad population

Last reviewed: June 27, 2026 Last updated: June 27, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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Similar to our primary analysis, we calculated 3 different comorbidity scores: the VHA frailty index 60 , the weighted CCI 61,62 ,and cardiovascular risk as calculated by DAgostino method 63

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