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Developing and refining preclinical models for early efficacy signals, developing and validating the bioanalytical assays necessary for quantitation, and designing the clinical studies that deliver the most robust data in this innovative therapeutic area are all key elements of a drug development program

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Samples with GLP-1R-high levels in both primary and metastatic tissue were enriched in genes involved in proliferation, tumor development, and multiple prognostic genes associated with other cancers ( Supplementary Figure 3a