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HIF- is the most well-known transcription factor activated in hypoxia

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DOI: 10.1210/jc.2005-1536 Ionescu M & Frohman LA (2006) Pulsatile Secretion of GH Persists During Continuous Stimulation by CJC-1295 J Clin Endocrinol Metab 91(12):47924797

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