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Reduced roGFP2 was oxidized much faster by GSSG in the presence of AtGrxS15 as compared with a negative control (Supplementary Fig
PMID: 38980576 | doi:10.1007/s10787-024-01499-8 Yarmola EG et al
They also reduce hepatic glucose output by decreasing hepatic FFA uptake and the expression of key gluconeogenesis enzymes such as PEPCK and G6Pase, while promoting hepatic sensitivity to insulin, transforming the liver from an "energy output organ" to an "energy storage organ"
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Not only GLP-1R, but also other incretin-related mRNAs (GLP-2R, GIPR, GlucagonR, proglucagon, GIP and DPPIV) were expressed in PSCs in sequential 14 passages (Figure 6c)
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