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During the Super Bowl, telehealth platform Hims & Hers released a controversial ad calling out drugmakers that provide weight loss drugs priced for profits, not patients. It then proceeded to highlight its compounded GLP-1 offerings, calling them affordable, doctor-trusted and formulated in the USA. Shortly after, Novo Nordisk responded to the ad with its own Check before you inject campaign, highlighting the argument that patients should be wary of compounded GLP-1s given that they arent FDA-approved products
doi:10.1056/NEJMoa2416394 Eli Lilly and Company
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This may have been due to a combination of a high affinity between the drug and the control antibody and lack of stability toward acid treatment leading to loss of functional control antibody
The FDA has received hundreds of adverse event reports tied to compounded semaglutide dosing errors, with some patients accidentally injecting five to twenty times their intended dose
Unlike endocrine peptides, GHK-Cu does not act through a single receptor system
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