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Retrieved 14 February 2026
If you've struggled to lose weight despite diet and exercise, the issue may not be willpowerit may be your hormones
Using data from STEP 1 and STEP 2, we found that semaglutide treatment reduced this CVD risk score compared with placebo (Fig
In fact, cardiovascular outcome trials demonstrated that subcutaneous semaglutide reduces major adverse cardiovascular events in high-risk populations, establishing cardiovascular safety and potential benefit
, hands [91]
However, their glucose-lowering efficacy may not be as strong as that of GLP-1 agonists like semaglutide
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