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DV: 5.2 mm, and for CA1 at AP: 3.24 mm

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2APB was dosed at 1 or 20 mg/kg and administered to mice 2 h before treatment with 500 mg/kg APAP

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Future research could explore combined delivery strategies for H and NO, or integrate ROS/pH-responsive modules to develop intelligent nanoscale systems capable of on-demand release and multi-mechanism synergistic precision therapy