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Hormonal birth control: If you are using an oral hormonal contraceptive (birth control), Zepbound may decrease its efficacy, especially after the first dose

Timing water intake strategically supports both hydration and digestion

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Patients who should NOT use it include those with uncontrolled diabetes, active malignancy or personal history of hormone-sensitive cancer, or pituitary disease

A special thanks to Hartmut Jaeschke and Anup Ramachandran from University of Kansas who have been generous in sharing several illustrations that I have significantly modified, but which saved weeks of time in preparation of this post

In all cases, mice were randomized according to body weight in each experimental group