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Accordingly, monitoring of total concentrations may be misleading since free concentrations may be substantially elevated in patients with hepatic disease whereas total concentrations may appear to be normal [seeBoxed Warning,Contraindications (4), andWarnings and Precautions (5.1)]
Tirzepatide, a dual GLP-1/GIP receptor agonist that has been approved for controlling blood sugar in T2DM, has emerging evidence suggesting that it is superior to GLP-1RAs in terms of glycemic control and weight loss (30, 31)
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