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A stable bedtime and wake-up schedule help keep these rhythms in sync, allowing the medication to work more effectively

Shauna Levy, a specialist in obesity medicine and medical director of the Tulane Bariatric and Weight Loss Center in New Orleans

Also pay attention to what to avoid

Eating less is not necessarily the problem on its own

Learn how Eden and Ro differ in the GLP-1 access and support services that they offer

This reframes the entire comparison: the relevant question is rarely how much weight can a drug take off in a year but how much can be kept off over a decade of continued, tolerable therapy. On that longer horizon, tirzepatide has actual data and retatrutide has, so far, only a promising short-to-medium-term trajectory