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In this article What Are GLP-1 Medications
Meals provide satisfaction without producing the cravings and preoccupation that make weight maintenance so difficult after traditional diets
However, insurance is less likely to cover them if prescribed for weight loss
15,23 This issue has been addressed by the synthesis of small molecule GLP-1RA that have smaller molecular sizes and can be administered orally offering a more convenient and acceptable option to patients
Lactic acidosis reports were markedly lower with combination therapy (567 vs 15,789), as were acute kidney injury (675 vs 7,694), diarrhoea (3,890 vs 6,922), and metabolic acidosis (203 vs 4,713), suggesting that the addition of GLP-1 RAs to metformin may mitigate serious adverse effects associated with metformin alone (Table 2)
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