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The glucagon-like peptide 1 (GLP-1) signaling pathway has emerged as a key mediator of metabolic-immune communication with neuroprotective properties

Constitutively stabilized NRF2 also promotes cell proliferation, as NRF2 knockdown inhibits the proliferation of human lung cancer cell lines (Singh et al., 2008)

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Renal cysteine conjugate -lyase-mediated toxicity studied with primary cultures of human proximal tubular cells

However, none included a direct assessment of renal fibrosis