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Particles in good 2D classes were chosen (1,367,618 in total) for 3D classification using an initial model generated from a subset of the particles in RELION

Though initially created as diabetes treatments to control blood glucose in type 2 diabetic patients, these drugs offer the same blood sugar regulating advantages even when prescribed to people without diabetes who take them primarily for weight management

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NOTE: Always get physician approval before starting or stopping any medication therapies for safety and health reasons

GLP-1 receptors were detected through immunohistochemistry in CSMCs of mice, suggesting that GLP-1 RAs may act directly on CSMCs (Richards et al., 2014)