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What the research shows Use of GLP1 medications has expanded rapidly, yet according to Wood, clinical studies have not demonstrated a clear increase in kidney stone formation among people taking them
It should be noted that this study was funded by Novo Nordisk, the pharmaceutical company that produces semaglutide
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Some providers prescribe it off-label for weight loss, though the oral bioavailability is lower and the weight loss results are typically more modest than the injectable form
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The first and original use is for type 2 diabetes management , where GLP-1 agonists help lower hemoglobin A1c levels by 1.02.0% on average, with the additional benefit of promoting modest weight loss rather than weight gain seen with some other diabetes medications
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