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Upregulation of Growth Factors: It increases the expression of receptors for growth factors (like VEGF ), accelerating the rate at which fibroblasts (collagen-producing cells) do their work

At 3 months, 59% of the MPT group reported moderate or marked improvement compared to 26% in the GTM group a statistically significant difference

Oxycodone is an even more potent painkiller than hydrocodone, and its chronic use or misuse contributes to the current opioid epidemic

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6-month duration may not capture full benefit