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Spironolactone (0, 100 nM, 1 M, 10 M, 30 min) inhibits Ang II-induced inflammation [5]

Glutathione is a natural antioxidant found in our body, produced by the liver

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Compound 36 also exhibited good efficacy in oral glucose tolerance tests, demonstrating great DPP-4 inhibitory activity (IC 50 = 0.017 M) and moderate selectivity against DPP-4 in both ICR and KKAy mice

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death