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We used an existing PKPD model of semaglutide [16] and an existing PK model of tirzepatide [19]
GLP-1 is one hormone signaling pathway useful for therapeutic intervention 21 , although the exact mechanism of action has yet to be completely elucidated
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Semaglutide is a highly complex molecule as it is a peptide, and is comprised of a chain of 31 amino acids including some non-natural amino acids and some additional chemical modifications to modify performance
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