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It appears that each melanocyte is in contact with about 35 neighbouring keratinocytes in the basal and suprabasal cell layers of the epithelium, each forming a melanocyte-keratinocyte unit [4, 6, 7]

Arisi et al., 1997)
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A glossy and swollen tongue This sign is not limited to the face, but it becomes noticeable when examining the mouth and the surrounding facial area

dose reduction of these medications may be needed) [1] Acute kidney injury risk, particularly with severe gastrointestinal adverse reactions causing dehydration Diabetic retinopathy complications , particularly in patients with a history of retinopathy who experience rapid improvement in blood glucose [1] Acute gallbladder disease including cholelithiasis and cholecystitis The FDA label includes a boxed warning about thyroid C-cell tumors observed in rodent studies, though the relevance to humans remains uncertain

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