nejm semaglutide ckd flow trial kidney outcomes hazard ratio 0.76 2024 Study: Semaglutide slowed progression of CKD, cut cardiovascular events, mortality risk 🚨 Journal Club: FLOW Trial – A comparison of the effects – In adults with type 1

However, athletes considering these medications primarily for body composition changes (rather than health-related weight loss) should understand that muscle preservation requires deliberate, intensive effort

Safety & Side Effects Are GLP-1 treatments safe

Despite the pleiotropic properties of GLP-1, including its insulinotropic effect found in rats, pigs, and humans, its extremely short plasma half-life of less than 2 minutes constituted a huge brick wall in the path of GLP-1 to be developed as a glucose-lowering medication

This protective effect is crucial for maintaining overall health and may play a role in preventing various chronic conditions

Fractures involve bone damage and often accompany severe ligament injuries

However, at this stage, we do not yet have sufficient high-quality human data to fully understand the safety, efficacy, and long-term effects of BPC-157