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The medicine works by sending signals to the appetite center in your brain to reduce hunger

Layering a second incretin agonist on top of Retatrutide does not add a new mechanism it doubles down on receptors the triple agonist already saturates, so the predictable result is additive gastrointestinal load and, if either agent has glucose-lowering partners on board, additive hypoglycemia risk

For most people, taste changes are simply another temporary adjustment as the body responds to Mounjaro