As GLP-1 medications such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) become more widely prescribed for weight loss, questions about nutrient depletion and vitamin requirements have increased
Additionally, co-agonism of MC4R and MC3R may enable 3 rd -generation melanocortin agonists to access a wider patient population in general obesity
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Bone Health and Muscle Preservation Weight loss, especially rapid weight loss, can lead to loss of lean muscle mass and changes in bone density
doi:10.1056/NEJMoa1612917 9
Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, et al