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GLP-1s drop hs-CRP substantially

This is a well-documented clinical problem because the consequences of faster insulin absorption are more immediately dangerous than faster semaglutide absorption

A claims-based analysis of 4,066 commercially insured adults with obesity newly initiating GLP-1 therapy without a diabetes diagnosis found that overall persistence dropped to 46.3% at 180 days and just 32.3% at one year

Emerging evidence suggests the relationship between GLP-1 receptor agonists and atrial fibrillation may be more clinically relevant than previously thought

N Engl J Med (2008) 358(6):58091