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Tumorigenesis-associated metabolic reprogramming affects the genomic status by regulating the enzymes for epigenetic modifications, which commonly utilize key metabolites as either substrates or allosteric regulators (Etchegaray and Mostoslavsky, 2016
Retrieved 27 August 2017
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Loss of pancreatic -cell identity, increased -cell identity, -cell number and glucagon content, and elevated expression of dedifferentiation markers
Lancet (2019) 394(10193):1318
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