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The rapid weight loss from GLP-1s can cause gallbladder problems, and muscle mass loss called sarcopenia

Journal of Clinical Investigation, 103(1), 1928

For type 2 diabetes (NICE NG28), they are typically used when patients have not achieved adequate control with metformin and lifestyle modifications

The results showed that both models had elevated ferroptosis, with downregulated ALKBH5 and upregulated YTHDF1 and ACSL4

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