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The CIS20r fatigue scale was 51 6 pretreatment and 50 6 posttreatment, and the CIS20r concentration scales were both 28 6 pretreatment and posttreatment
Liver enzyme elevations (ALT and AST above 3 times the upper limit of normal) occurred at rates similar between orforglipron and placebo groups, with no dose-dependent pattern suggesting drug-related hepatotoxicity
Muscle Loss : Not all weight loss is beneficialsome studies indicate that lean body mass (muscle) can be lost too, potentially resulting in a lower metabolism and making maintenance challenging
PMID 38753454
Any use outside approved indications would be considered off-label prescribing, which requires careful clinical justification and informed patient consent
Day 6 About 110 g protein Breakfast 32 g Overnight oats with Greek yogurt, protein powder, oats, and berries
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