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NAD + is essential to life and loss of it as we age reduces our bodys abilities to regenerate or repair itself at the cellular level and maintain mitochondrial health

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Biosci Rep (2019) 39(7):3245-58

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By activating the antioxidant pathway Nrf2, they enhance the activity of enzymes like superoxide dismutase (SOD), reduce the expression of cyclooxygenase-2 (COX-2), and alleviate oxidative stress damage to the immune system 128

[4] In case of accidental large overdose (e.g., someone receives far more frequent injections than prescribed), monitoring for symptoms like flushing, tingling in extremities, or liver enzyme elevations would be prudent