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Retatrutide is an investigational triple incretin receptor agonist under clinical development by Eli Lilly, whilst 5-Amino-1MQ is a research chemical targeting the NNMT enzyme

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31,32 The recognition that modification of LDL is an initiator of endothelial damage allows for a clearer understanding of LDLs role in the grand scheme of heart disease

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doi: 10.1016/j.biopha.2019.109552, 17