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The active site in each subunit is known to be composed of two definite functional regions
Although these lesions can also occur spontaneously in different rodents with different diseases or with certain neoplasms causing hemodynamic changes, it can also be induced by different compounds
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Previously, SHMT2 expression has been shown to be inversely associated with tumor-infiltrating lymphocytes in the tumor microenvironment of patients with lung adenocarcinoma, using TIMER and TISIDB online databases [73, 74]
