Leptin resistance where the hypothalamus no longer responds appropriately to adipokine signals is a hallmark of established obesity, as described in StatPearls (NCBI)
"As dermatologists, we frequently see the physical consequences, including damaged nail plates, chronic inflammation around the nails, infections, and permanent nail changes." Now, there's still a lot we don't know about how and why GLP-1 medications work and why people experience such diverse side effects, but physicians have some theories as to why injecting yourself with semaglutide or tirzepatide might make you less likely to chomp on your fingernails
In plain language, it slows down how quickly your body breaks down and absorbs carbohydrates from food
For example, if your protocol calls for 250mcg daily for 30 days, and you reconstituted with 2 mL of bacteriostatic water, each 0.1 mL withdrawal contains a specific amount
10.1038/srep10147 181 XuB.O'DonnellM.O'DonnellJ.YuJ.ZhangY.SartorM
If I want to have my teen evaluated for a possible GLP-1 prescription, where do I start