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Kim and Ashley A
Improves Metabolic Health Lipedema is frequently linked to metabolic conditions like insulin resistance
The most common adverse effects reported across the 4-mg, 9-mg, and 12-mg retatrutide groups, compared with placebo, were: Nausea: reported by 28.6%, 38.4%, and 42.4% of retatrutide participants, respectively, compared with 14.8% for placebo Diarrhea: reported by 25.2%, 34.1%, and 32.0% of retatrutide participants compared with 13.5% for placebo Constipation: reported by 23.8%, 25.9%, and 26.1% of retatrutide participants compared with 10.9% for placebo Vomiting: reported by 10.6%, 22.8%, and 25.3% of retatrutide participants compared with 4.8% for placebo Other observed adverse events included upper respiratory tract infections, urinary tract infections, and mild to moderate dysesthesia, although the majority of the urinary and neurological cases resolved during active treatment
With macrogol preparations, starting with one sachet daily and increasing to two or three sachets based on response is a sensible approach