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Saratov Med J
These drugs push body weight in opposite directions
Besides the respiratory physiology effect, a recent study proved that NMBA also plays an anti-inflammatory role by reducing several pro-inflammatory cytokines (IL-1, IL-6, and IL-8), which may favor its therapeutic effect (Forel et al., 2006)
This triple agonist design, developed by Eli Lilly under the research code LY3437943, represents a fundamentally different approach from semaglutide (which targets only GLP-1) or tirzepatide (which targets GLP-1 and GIP)
Nature Communications , 2026
That creates a dangerous mismatch
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