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Glutathione peroxidase, catalase, and superoxide dismutase activities relative to oxidative stress were highly suppressed in MP-exposed samples, accompanied by increasing reactive oxygen species (ROS) production and redox imbalance, as shown in the figure 2

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The most reported side effects include nausea, flushing, and headaches, which tend to be mild and short-lived

American Journal of Preventive Medicine, 55 (6), 864-874

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3, Oncogenic PI3K/AKT signaling stabilizes and activates nuclear factor erythroid 2related factor 2 (NRF2), a key regulator of antioxidant genes, driving upregulation of GSH biosynthetic enzymes