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Furthermore, a small population of PPG neurons has been identified within the olfactory bulb with only local projection (Thiebaud et al., 2016)
Phase 2 Trial Results (48 Weeks) The Phase 2 trial randomized 338 adults with obesity (BMI 30) or overweight with at least one weight-related condition to retatrutide or placebo for 48 weeks (Jastreboff et al., NEJM 2023)
Appetite Support May help support appetite regulation as part of a broader weight management plan
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Drugs with a glucagon-like peptide-1 (GLP-1) classification such as Novo Nordisk's Wegovy and Ozempic and Eli Lilly's Zepbound and Mounjaro, help in the regulation of digestion, appetite, and sugar which aid in weight loss
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