All strains were maintained on a C57BL/6 background
The table below summarizes typical pharmacokinetics for adult subcutaneous injection at standard doses (individual response varies with site, depth, dose, exercise, and renal function)
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McKie et al., 2005), and may be essential for ameliorating depressive behaviors
Long et al., 2024), including the NADPH/FSP1/CoQ10 pathway, the dihydroorotate dehydrogenase (DHODH) pathway, the GTP cyclohydrolase 1 (GCH1)/tetrahydrobiopterin (BH4)/dihydrofolate reductase (DHFR) pathway, the membrane-bound O-acyltransferase 1/2 (MBOAT1/2) pathway, the peroxiredoxin 6 (PRDX6) pathway, and the 7-dehydrocholesterol (7-DHC) pathway