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Those drugs mimic this hormone in a more sustained way than your body can on its own, since natural GLP-1 only sticks around in your bloodstream for a couple of minutes

[24] In 2020, the FDA approved two higher doses of the medication, 3.0 mg and 4.5 mg, based on results of the AWARD-11 trial demonstrating improved glucose lowering and weight benefits

This notable effect results from combined mechanisms that address appetite, satiety, gastric emptying, and glucose body function through multiple receptor systems, creating full effects that exceed simple addition of personal peptide effects

Gao X., Tian Y., Randell E., Zhou H., Sun G