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Moreover, vitamin C enhances neutrophil and lymphocyte activity, limits neutrophil necrosis and extracellular trap formation, and modulates nuclear responses to hypoxia and stress by regulating HIF-1 and inducing NF-B-related epigenetic changes (Fisher et al., 2011

In animal wound models, it accelerated healing and reduced inflammation, suggesting applications for joint, tendon, and soft-tissue repair

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But "natural" doesn't automatically mean safe, and "synthetic" doesn't automatically mean dangerous

Awasthi S et al

The vehicle (carrier) matters as much as the concentration for skin penetration