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Limited human data exists, mostly anecdotal reports and case observations, and no controlled clinical trials have confirmed direct muscle growth or hypertrophy benefits

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Experimental models have examined its influence on vascular endothelial growth factor receptor-2 (VEGFR2) signaling, including activation of downstream VEGFR2AkteNOS pathways associated with endothelial cell proliferation and vascular signaling processes

Human data are still limited, and long-term safety is unknown

Each of these small missteps dramatically increases the risk of introducing bacteria