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Franzke et al., 2018
The research aimed to inhibit the ISR-inducing double-stranded RNA-activated protein kinase by enhancing the function of the eukaryotic translation initiation factor 2-eukaryotic translation initiation factor 2B complex (eIF2-eIF2B)
Cancer 68, 554559
That is a daily dose more than ten times the weekly injectable dose, and even then, the clinical results are roughly equivalent, not superior
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The number of GA (genetic algorithm) runs was set to 30
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