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SURPASS-5 examined tirzepatide added to insulin glargine in patients with advanced diabetes
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Then on June 29, 2026, Health Canada approved Sevmia, the first generic semaglutide indicated for chronic weight management, the equivalent of generic Wegovy
Cagnacci, A., & Venier, M
In humans, coadministration of the GLP-1 agonist semaglutide with the amylin agonist cagrilintide produced ~ 24% body-weight reduction in overweight or obese adults, comparable to the most potent current therapies [121]
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