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Glutathione is often called the master antioxidant. That phrase captures its importance, but its real biology is more sophisticated: it operates as part of a coordinated network with glutathione peroxidases, glutathione reductase, glutaredoxins, NADPH and many other protective systems

Chronic unpredictable stress, considered a model of depression, results in a reduction in dendritic lengths and branching of apical dendrites, the loss of functional synaptic spines, and the reduction of dendritic complexity in PFC neurons and in the hippocampal CA3 pyramidal neuronal cell layer (McEwen et al., 2012

The ulcers develop from a combination of factors, including decreased blood flow to the mucosa causing ischemia and hypoperfusion-reperfusion injury

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