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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone
Basic metabolic panel and lipid panel Baseline plus periodic review at 4-week and 8-week marks
CoQ10 does not interact with other common antihypertensives (lisinopril, losartan, hydrochlorothiazide, metoprolol) through CYP-mediated mechanisms
Comput Biol Chem
2020, Oct;172:106124 Blatnik M, Thorpe SR, Baynes JW
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