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Incretin triple agonist retatrutide (LY3437943) alleviates obesity-associated cancer progression

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Scores on the Three-Factor Eating Questionnaire (TFEQ-R18) improved in all treatment groups, with Cagrilintide producing greater improvements than placebo in specific domains: cognitive restraint, notably at 1.2 mg and 4.5 mg, emotional eating notably at 0.3 mg and 2.4 mg, and uncontrolled eating notably at 1.24.5 mg

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Analyses of human insulitis lesions have suggested that signals released from stressed -cells precedes, and putatively initiates, the development of insulitis (31)

doi:10.1016/j.biopsych.2011.10.024