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J Innate Immun

ME/CFS, FM, and GWS were selected for this review due to (i) the common overlap of ME/CFS and FM where similar biological dysfunction might be expected and (ii) GWS, with its identifiable and specific trigger, likely to offer a different biological perspective

Ermert (Khondrion BV, Nijmegen

B.AdlerD

Environmental toxins and pesticides exacerbate the pathological process by triggering ferroptosisa form of iron-dependent cell deathand contributing to synuclein aggregation

The page-specific claim focus is: Injectable reduced glutathione (GSH) is used in some clinical settings due to poor oral bioavailability, but the compound is highly unstable in aqueous solution and converts to its oxidized form (GSSG) over time, reducing therapeutic activity