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Key Points Compounded semaglutide uses the same active ingredient as Ozempic and Wegovy, but is made by specialized pharmacies The FDA banned compounded versions in May 2025 after declaring the Ozempic shortage resolved, with rare exceptions only for specific medical needs Safety risks include inconsistent dosing between batches, potential contamination, and a lack of robust clinical trial data Insurance rarely covers compounded versions, while brand-name medications offer manufacturer savings programs that reduce monthly costs In early 2022, millions of people were unable to find their prescribed Ozempic and Wegovy medications anywhere

10.1016/j.bbrc.2017.11.114 Biochem

I did some studies looking at pregnancy after bariatric surgery, says Kate Maslin, a research fellow in maternal and child health at the University of Plymouth in England

A microdose might slow but not prevent this regain

Frequently Asked Questions Are Compounded GLP-1's Approved

AstraZeneca funded the trial, and the funder contributed to the study design, conduct, data collection, analysis, interpretation, and report writing