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Although some improvements in pigmentation were observed in subgroups, results were mixed and highlighted the need for consistent use and further research Health+15CDEK Pharmacy+15ClinicalTrials.gov+15

[6] Beyond pigmentary effects, the gray-market literature also describes nausea and facial flushing, spontaneous penile erection (priapism, an MC4R-mediated effect), and occasional systemic reactions such as rhabdomyolysis

They chose yellow-haired mice, which were specially bred to have defects in the same gene causing red hair and easily-burned skin in humans

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