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[4] As another GLP-1 receptor agonist, it has a similar gastrointestinal side effect profile to liraglutide and the same cautions would apply regarding use in inflammatory bowel disease

Gastrointestinal Side Effects The most common side effects of GLP-1 medications are gastrointestinal, including nausea, diarrhea, vomiting, constipation, and abdominal discomfort

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If muscle pain persists despite optimization of all modifiable factors, a trial of semaglutide or another GLP-1 agonist may be reasonable

Sources: 1 Medication Containing Semaglutide Marketed for Type 2 Diabetes or Weight Loss FDA 2 GLP-1 agonists: Diabetes drugs and weight loss Mayo Clinic 3 GLP-1 Drugs Comparison GoodRx FDA Drug Release Info: Adlyxin: FDA approves Adlyxin to treat type 2 diabetes | FDA Byetta: Drug Approval Package: Byetta (Exenatide) NDA #021773 (fda.gov) Mounjaro: FDA Approves Novel, Dual-Targeted Treatment for Type 2 Diabetes | FDA Ozempic: FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 FDA Rybelsus: FDA approves first oral GLP-1 treatment for type 2 diabetes FDA Saxenda: FDA approves weight management drug for patients aged 12 and older | FDA Trulicity: FDA Drug Approval Package Victoza: FDA Drug Apprival Package Wegovy: FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014

Hemodynamic study of intravenous propionyl-L-carnitine in patients with ischemic heart disease and normal left ventricular function