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After 8 weeks of the HFD, the HFD + NaB group underwent daily intragastric administration of NaB at 200 mg/kg body weight for 8 weeks, while the HFD group received the same amount of saline daily for 8 weeks
However, glutathiones relative distribution within cells is difficult to determine because oxidized glutathione (GSSH) rapidly recycles back to reduced glutathione (GSH)
Maresh, Metabolism 59 (2010) 11901199
That is not the issue
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Furthermore, for specific compounds, additional key mechanisms such as Fas-mediated signal transduction, loss of cellular redox homeostasis, ATP depletion, changes in ion channels, and activation of kinases and caspases, among others, have been highlighted
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