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In these cases, hydroxocobalamin or adenosylcobalamin may be better tolerated, as they provide B12 support without strongly stimulating methylation

Because sufficient amounts of IF are needed to bind to B12, and adequate stomach acid is required to activate IF, a deficiency of either can lead to a B12 deficiency and devastating health consequences

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If you suspect you have a vitamin B12 deficiency, it's important to consult your GP for proper diagnosis and investigation of the underlying cause before starting treatment

Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006) and is currently supported by the Wellcome Trust [216767/Z/19/Z]

"It might be a substance that your body has never seen before, so you mount an immune response and it can have unintended side effects on many parts of your body that can be potentially even fatal